An elephant’s trunk has 40,000 muscles and weighs more than a Burmese python. The appendage is strong enough to uproot a tree, yet sensitive enough to suction up fragile tortilla chips.

But how does an elephant’s brain help accomplish these feats of dexterity? That has been difficult to study, according to Michael Brecht, a neuroscientist at the Humboldt University of Berlin. Weighing in excess of 10 pounds, the elephant’s brain degrades quickly after death and is a hassle to store. “I tend to think that the big animals are a bit neglected because we don’t do enough work on big brains,” Dr. Brecht said.

Dr. Brecht and his colleagues were fortunate enough to gain access to a trove of elephant brains from animals that had died of natural causes or were euthanized for health reasons and ended up either frozen or in a fixative substance at the Leibniz Institute for Zoo and Wildlife Research in Berlin.

In a study published Wednesday in the journal Science Advances, Dr. Brecht and his colleagues reported that elephants had more facial neurons than any other land mammal, which might contribute to trunk dexterity and other anatomical abilities. The study also helped to pinpoint major differences between the neural wirings of African savanna elephants and Asian elephants.

The researchers divided the facial nucleus into regions of neurons that controlled the elephant’s ears, lips and trunk. African elephants sported 63,000 facial neurons, while their Asian cousins had 54,000. The only mammals with more are dolphins, which pack nearly 90,000 facial neurons into their sensitive snouts.

While his team expected both African savanna and Asian elephants to possess massive stores of facial neurons, Dr. Brecht said the discrepancy between the two species was noteworthy.

Another major difference is how each elephant wields its trunk, which requires nearly half of the elephant’s total facial neurons to operate. African elephants utilize two fingerlike projections on the tips of their trunks to pinch objects, like the motion made with a pair of chopsticks. Asian elephants have only one fingerlike projection and grasp objects by wrapping their trunks around them. The researchers pinpointed two neural regions in African elephants that probably correlated to fine finger control at the tips of their trunks; those regions were less defined in Asian elephants.

While defining the roles of various parts of the sprawling network of the elephant’s facial nucleus is valuable, Suzana Herculano-Houzel, a neuroscientist at Vanderbilt University who was not involved in the new study, thinks the number of neurons is unsurprising for such a mammoth mammal.

Other parts of the elephant brain are also impressive, she said. Dr. Herculano-Houzel has shown in her research that the elephant’s cerebellum, the brain region that controls motor functions, has 12 times as many neurons than expected for a mammal of its size. “The elephant’s cerebellum is stratospheric compared to all of the other mammals,” she said.

While the facial neurons may not be off the charts by comparison, Dr. Brecht believes a better understanding of these structures in elephants can provide insights into other large mammals — including humans.

“Although we’re not as big as elephants, we’re still quite big,” he said, and these are patterns “that you probably would not see in a mouse.”